[内容简介]
An Introduction to Bioinformatics is intended to be a complete study companion for the advanced undergraduate or beginning graduate student. It is self-contained in the sense that whatever the starting point may be, the reader will gain insight into bioinformatics. Underlying the work is the belief that bioinformatics is a kind of metaphoric lens through which the entire field of biology can be brought into focus, admittedly as yet imperfect, and understood in a unified way. Reflecting the highly incomplete present state of the field, emphasis is placed on the underlying fundamentals and acquisitions of a broad and comprehensive grasp of the field as a whole.
[目次]
Preface.
1. Introduction.
I: Information.
2. The nature of information.
3. The transmission of information.
4. Sets and combinatorics.
5. Probability and likelihood.
6. Randomness and complexity.
7. Systems, networks and circuits. II: Biology.
8. Introduction to part
II.9. The nature of living things.
10. The molecules of life.
III: Applications.
11. Introduction to part
III. 12. Genomics.
13. Proteomics.
14. Interactions.
15. Metabolomics and metabonomics.
16. Medical applications. Bibliography.