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Bio-interactions of Nano Materials
发布日期:2015-12-08  浏览

Bio-interactions of Nano Materials

[Book Description]

An examination of the widespread application of nano materials in biology, medicine, and pharmaceuticals and the accompanying safety concerns, Bio-interactions of Nano Materials addresses the issues related to toxicity and safety of nano materials and nano systems. It covers the interactions in biological systems and presents various tools and methods used to evaluate the nano toxicity and nano safety issues. Written by leading scientists, the book focuses on the bio-interaction of nano materials, covering various techniques and tests which have been developed to evaluate the toxicity of materials at the nano level. The book highlights the challenges of bio-interactions of nano materials and possible solutions to those challenges. It addresses the assessment and characterization of nano systems in bio-environments, toxicity and bio-sensing devices for toxicity assessment, carbon nano tubes and pulmonary toxicity, and nano toxicity of solid lipid nanoparticles. It also discusses nano safety concerns and solutions, including the effects of nano particles on different organs and regulatory implications of nano materials.These particles may be used to encapsulate drugs, recognize biological markers, or visualize body tissues among many other possibilities, all enabling their widespread application in biology, medicine, and pharmaceutics. Indeed, these nano materials may have beneficial effects that have not even been imagined. This book gives you an understanding of the safety issues, how to assess for them, and how to mitigate them to move forward in research and development of new applications for nano materials.

[Table of Contents]
 
Foreword                                           ix
Preface                                            xi
Editors                                            xiii
Contributors                                       xv
    Chapter 1 Introduction---Biointeractions of    1   (48)
    Nanomaterials: Challenges and Solutions
          Vijaykumar B. Sutariya
          Vrinda Pathak
          Ana Groshev
          Mahavir B. Chougule
          Sachin Naik
          Deepa Patel
          Yashwant Pathak
    Chapter 2 Nanoparticle Exposures in            49  (24)
    Occupational Environments
          Li-Hao Young
          Ying-Fang Wang
          Ching-Hwa Chen
          Chun-Wan Chen
          Perng-Jy Tsai
    Chapter 3 Physicochemical                      73  (30)
    Characterization-Dependent Toxicity of
    Nanoparticles
          Jigar N. Shah
          Ankur P. Shah
          Hiral J. Shah
          Vijaykumar B. Sutariya
    Chapter 4 Cytotoxicity of                      103 (14)
    Stimuli-Responsive Nanomaterials:
    Predicting Clinical Viability through
    Robust Biocompatibility Profiles
          Daniel Wehrung
          Moses O. Oyewumi
    Chapter 5 Biosensing Devices for Toxicity      117 (14)
    Assessment of Nanomaterials
          Evangelia Hondroulis
          Pratik Shah
          Xuena Zhu
          Chen-Thong Li
    Chapter 6 Carbon Nanotubes and Pulmonary       131 (10)
    Toxicity
          Malay K. Das
          Charles Preuss
    Chapter 7 Nanotoxicity of Polymeric and        141 (18)
    Solid Lipid Nanoparticles
          Dev Prasad
          Harsh Chauhan
    Chapter 8 Analytical Characterization of       159 (16)
    Nanomaterials in Biological Matrices for
    Hazard Assessment
          Mingsheng Xu
          Daisuke Fujita
          Huanxing Su
          Hongzheng Chen
          Nobutaka Hanagata
    Chapter 9 Nanoparticles and Human Health: A    175 (34)
    Review of Epidemiological Studies
          Vijaykumar B. Sutariya
          Ana Groshev
          Vivek Dave
          Hardeep Saluja
          Deepak Bhatia
          Prabodh Sadana
          Yashwant Pathak
    Chapter 10 Toxicogenomic Approaches to         209 (16)
    Understanding the Toxicity of Nanoparticles
          Qiwen Shi
          Mahavir B. Chougule
          Vijaykumar B. Sutariya
          Deepak Bhatia
    Chapter 11 Nanomaterial-Based Gene and Drug    225 (24)
    Delivery: Pulmonary Toxicity Considerations
          Mahavir B. Chougule
          Rakesh K. Tekade
          Peter R. Hoffmann
          Deepak Bhatia
          Vijaykumar B. Sutariya
          Yashwant Pathak
    Chapter 12 Cardiovascular Toxicity of          249 (10)
    Nanomaterials
          Saijie Zhu
          Minghuang Hong
    Chapter 13 Toxicity of Nanomaterials on the    259 (26)
    Gastrointestinal Tract
          Jayvadan Patel
          Vibha Champavat
    Chapter 14 Toxicity of Nanomaterials on the    285 (30)
    Liver, Kidney, and Spleen
          Jayvadan Patel
          Anita Patel
    Chapter 15 Regulatory Implications of          315 (32)
    Nanotechnology
          Lynn L. Bergeson
          Michael F. Cole
    Chapter 16 Ocular Toxicity of Nanoparticles    347 (6)
          Aditya Grover
          Anjali Hirani
          Yong Woo Lee
          Vijaykumar B. Sutariya
          Yashwant Pathak
    Chapter 17 Genotoxicity of Nanoparticles       353 (12)
          Amaya Azqueta
          Leire Arbillaga
          Adela Lopez de Cerain
    Chapter 18 Interactions of                     365 (18)
    Polysaccharide-Coated Nanoparticles with
    Proteins
          Christine Vauthier
    Chapter 19 Models for Risk Assessments of      383 (42)
    Nanoparticles
          Sanjay Dey
          Bhaskar Mazumder
          Yaswant Pathak
    Chapter 20 Immunotoxicity of Carbon            425 (18)
    Nanoparticles
          Paulami Pal
          Bhaskar Mazumder
          Yaswant Pathak
Index                                              443

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